Man City defeated Urawa to reach the 'once-in-a-lifetime' final
Guardiola's team swept past Urawa Red Diamonds in Tuesday's semi-final to set up a meeting with the South American champions on Friday in Saudi Arabia.
City are looking to become the fourth English club to win the title after Manchester United, Liverpool and Chelsea.
"The players know how important it is for the club," said Guardiola.
"To be in this final, you must do incredible things like win the Champions League. This may be the only time we play this in our lifetime.
"We are there. We will try to win a title we don't have and finish the circle."
The Spaniard has previously won the competition twice while Barcelona boss and once during his three-year tenure at Bayern Munich.
And the odds of him adding to that collection seem short, given how City comfortably defeated the Asian champions Urawa.
The Japanese club displayed plenty of defensive resilience until defender Marius Hoibraten turned Matheus Nunes' cross into his net on the stroke of halftime.
However, after the break, it was a different story, with Mateo Kovacic quickly adding City's second - running through the heart of an absent Urawa defence to latch on to Kyle Walker's pass and lift his effort past goalkeeper Shusaku Nishikawa.
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